Centellian24

Madeca Cream Time Reverse Zero

The Centellian24 Madeca Cream Time Reverse Zero is an advanced, age-defying recovery moisturizer developed by Dongguk Pharmaceutical. This upgraded version of Korea’s iconic “ointment cream” combines high-concentration TECA (Titrated Extract of Centella Asiatica) with Retinol, Collagen, and Elastin to actively reverse signs of structural aging while maintaining a healthy, calm skin barrier.

Skin Type

Acne, Combination Skin, Dry Skin, Mature Skin, Sensitive Skin

Routine Step

4. Moisturizer

Cruelty-free

Yes

Price range: € 5,95 through € 18,75

This sophisticated formula elevates the classic healing powers of Cica into an intensive anti-aging shield.

It features a cushioning, creamy texture that spreads fluidly and absorbs without the heavy, stifling weight of traditional anti-wrinkle balms. Backed by pharmaceutical-grade science, it utilizes micro-encapsulated TECA to soothe surface inflammation and rapidly repair compromised lipid layers. At the same time, its cellular-renewing blend of low-molecular collagen, elastin, and a touch of retinol works systematically to plump sagging contours and smooth out expression lines.

It leaves the skin feeling exceptionally bouncy, balanced, and wrapped in a healthy, dewy radiance.

Ideal for: Deep Barrier Reconstruction, Expression Line Smoothing, Instant Redness Relief, Skin Density Boosting, Post-Retinoid Recovery.

  1. Use morning and evening as the final moisturizing step of your skincare routine.
  2. Squeeze an appropriate amount from the soft plastic tube onto clean fingertips.
  3. Smooth evenly over the face and neck, pressing gently from the center outwards.
  4. Allow a few moments for the cream to absorb completely into your skin matrix.
  5. Pro Tip: This cream serves as a fantastic “recovery companion”. Apply a slightly thicker layer on nights when your skin feels irritated from active chemical exfoliants, travel, or dry weather to wake up to a completely restored complexion.
  6. Note: Features a mild, natural herbal aroma from the pure Centella extracts that dissipates quickly upon absorption.

Water, Dipropylene Glycol, 2,3-Butanediol, Hydrogenated Poly(C6-14 Olefin), Caprylic/Capric Triglyceride, Niacinamide, Isodecyl Neopentanoate, Glyceryl Stearate, Polyglyceryl-6 Distearate, Cetearyl Alcohol, Vinyl Dimethicone, Dicaprylyl Ether, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, 1,2-Hexanediol, Sodium Polyacryloyldimethyl Taurate, Centella Asiatica Leaf Extract, Centella Asiatica Oil, Asiaticoside, Asiatic Acid, Madecassic Acid, Madecassoside, Hydrolyzed Hyaluronic Acid, Ceramide NP, Collagen Amino Acids, Hydrolyzed Elastin, Retinol, Ectoin, Resveratrol, Adenosine, Allantoin, Panthenol, Glycerin, Macadamia Ternifolia Seed Oil, Glycine Soja (Soybean) Oil, Hydrogenated Lecithin, Phytosphingosine, Lauric Acid, Disodium EDTA, Ethylhexylglycerin.

50 Years of Pharmaceutical Expertise for 24-Hour Skin Care.

Centellian24 is a high-performance Korean derma-cosmetic brand born from the specialized expertise of Dongkook Pharmaceutical, a leader in skin science since 1968. The brand’s name combines “Centella Asiatica”—their hero ingredient—with “24,” representing their commitment to protecting and revitalizing your skin 24 hours a day. By leveraging pharmaceutical-grade technology, Centellian24 delivers clinical results designed to bridge the gap between medicine and daily beauty.

The brand’s secret lies in its proprietary TECA (Titrated Extract of Centella Asiatica). Unlike standard Centella extracts, TECA is a highly concentrated, purified active ingredient developed through a fastidious 7-step extraction process. This “Golden Ratio” of Centella compounds is scientifically proven to stimulate collagen synthesis, repair the skin barrier, and soothe extreme irritation.

Whether you are dealing with the first signs of aging or seeking intensive recovery for stressed skin, Centellian24 provides honest, science-backed solutions that prioritize efficacy and stability. Experience the power of pharmaceutical-grade Centella and discover why Centellian24 remains Korea’s #1 choice for derma-aesthetic care.

Key Ingredients


Active-TECA™ :

Ectoin & Resveratrol:

Niacinamide & Adenosine:

Collagen Amino Acids & Hydrolyzed Elastin:

Ceramide NP & Phytosphingosine:

Micro-Dosed Retinol:

Key Ingredients


Active-TECA™ :

A highly-purified, pharmaceutical-grade Centella extract that actively stimulates collagen and rapidly repairs damaged skin.

Ectoin & Resveratrol:

Elite antioxidants that protect fragile cells from environmental stressors, urban pollution, and blue-light fatigue.

Niacinamide & Adenosine:

Functional powerhouses that visibly brighten dark spots and smooth stubborn wrinkles.

Collagen Amino Acids & Hydrolyzed Elastin:

Low-molecular structural proteins that effectively cushion the intercellular matrix, enhancing surface bounce.

Ceramide NP & Phytosphingosine:

Essential lipid components that systematically rebuild a broken moisture barrier to lock down 24-hour hydration.

Micro-Dosed Retinol:

Positioned at the base of the formula to gently assist surface cell turnover without triggering typical retinoid flaking.

Linked Products:


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